Maleimide
Names
[ CAS No. ]:
541-59-3
[ Name ]:
Maleimide
[Synonym ]:
maleic acid imide
monomaleimide
Maleic imide
EINECS 208-787-4
1H-Pyrrole-2.5-dione
3-pyrroline-2,5-dione
Maleimide
Maleinimide
pyrroline-2,5-dion
2,5-Pyrroledione
1H-Pyrrole-2,5-dione
N-hydroxysuccinimide
MFCD00005494
Pyrrole-2,5-dione
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
264.4±23.0 °C at 760 mmHg
[ Melting Point ]:
91-93 °C(lit.)
[ Molecular Formula ]:
C4H3NO2
[ Molecular Weight ]:
97.072
[ Flash Point ]:
113.7±22.6 °C
[ Exact Mass ]:
97.016380
[ PSA ]:
46.17000
[ LogP ]:
-0.69
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.606
[ Storage condition ]:
Refrigerator
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ON4800000
- CHEMICAL NAME :
- Maleimide
- CAS REGISTRY NUMBER :
- 541-59-3
- BEILSTEIN REFERENCE NO. :
- 0106910
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C4-H3-N-O2
- MOLECULAR WEIGHT :
- 97.08
- WISWESSER LINE NOTATION :
- T5VMVJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(11),109,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7766 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - hemorrhage Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - other changes
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,151,1978 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 750 ug/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 3100 ug/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 37,15,1976
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H314-H317
[ Precautionary Statements ]:
P280-P301 + P310-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R25;R36/37/38;R43
[ Safety Phrases ]:
S26-S36/37/39-S45-S37/39-S28A
[ RIDADR ]:
UN 2923 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
ON4800000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
29251995
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
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