Hydrochloric acid

Hydrochloric acid Structure
Hydrochloric acid
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Common Name Hydrochloric acid
CAS Number 7647-01-0 Molecular Weight 36.461
Density 1.2 g/mL at 25 °C(lit.) Boiling Point -84.9±9.0 °C at 760 mmHg
Molecular Formula ClH Melting Point -35 °C
MSDSHydrochloric acid MSDS|SDS|pdf download Chinese USA Flash Point 无意义
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Controlled Substances:Psychoactive Drugs/Narcotic Drugs/Hypertoxic Chemicals/Non-Medical Use of Narcotic Drugs and Psychotropic Substances


 Names

[ Name ]: hydrogen chloride
[ Synonym ]: More Synonyms

 Chemical & Physical Properties

[ Density ]: 1.2 g/mL at 25 °C(lit.)
[ Boiling Point ]: -84.9±9.0 °C at 760 mmHg
[ Melting Point ]: -35 °C
[ Molecular Formula ]: ClH
[ Molecular Weight ]: 36.461
[ Flash Point ]: 无意义
[ Exact Mass ]: 35.976677
[ PSA ]: 0.80200
[ LogP ]: 0.00
[ Vapour density ]: 1.3 (vs air)
[ Vapour Pressure ]: 33917.9±0.1 mmHg at 25°C
[ Water Solubility ]: miscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MW4025000
CHEMICAL NAME :
Hydrochloric acid
CAS REGISTRY NUMBER :
7647-01-0
LAST UPDATED :
199712
DATA ITEMS CITED :
61
MOLECULAR FORMULA :
Cl-H
MOLECULAR WEIGHT :
36.46
WISWESSER LINE NOTATION :
H G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Rinsed with water
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
1300 ppm/30M
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
3000 ppm/5M
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
81 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3124 ppm/1H
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - iritis
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1108 ppm/1H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - respiratory stimulation Skin and Appendages - dermatitis, other (after systemic exposure)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40142 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4413 ppm/30M
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
4413 ppm/30M
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes Liver - other changes
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
685 ug/m3/24H/84D-C
TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
450 mg/m3/1H
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - homeostasis
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 225,55,1989 *** REVIEWS *** ACGIH TLV-CL 7.5 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,189,1992 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,189,1992 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,189,1992 TOXICOLOGY REVIEW ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 39,299,1978 TOXICOLOGY REVIEW AOHYA3 Annals of Occupational Hygiene. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,159,1974 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,163,1975 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD:air-CL 5 ppm (7 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,129,1971 OSHA PEL (Gen Indu):CL 5 ppm (7 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 5 ppm (7 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 5 ppm (7 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 5 ppm (7 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-BELGIUM:STEL 5 ppm (7.7 mg/m3) JAN 1993 OEL-DENMARK:STEL 5 ppm (7 mg/m3) JAN 1993 OEL-FINLAND:STEL 5 ppm (7 mg/m3);Skin JAN 1993 OEL-FRANCE:STEL 5 ppm (7.5 mg/m3) JAN 1993 OEL-GERMANY:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-HUNGARY:STEL 5 mg/m3 JAN 1993 OEL-JAPAN:STEL 5 ppm (7.5 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-POLAND:TWA 5 mg/m3 JAN 1993 OEL-RUSSIA:STEL 5 ppm (5 mg/m3) JAN 1993 OEL-SWEDEN:STEL 5 ppm (8 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (7.5 mg/m3);STEL 10 ppm (15 mg/m3) JAN 1993 OEL-THAILAND:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-TURKEY:TWA 5 ppm (7 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (7 mg/m3);STEL 5 ppm (7 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO HYDROGEN CHLORIDE-air:CL 5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 38580 No. of Facilities: 87434 (estimated) No. of Industries: 360 No. of Occupations: 156 No. of Employees: 824985 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 38580 No. of Facilities: 60309 (estimated) No. of Industries: 321 No. of Occupations: 183 No. of Employees: 1238572 (estimated) No. of Female Employees: 388130 (estimated)

 Safety Information

[ Symbol ]: GHS05 GHS07
GHS05, GHS07
[ Signal Word ]: Danger
[ Hazard Statements ]: H290-H314-H335
[ Supplemental HS ]: May form explosive peroxides., Repeated exposure may cause skin dryness or cracking.
[ Precautionary Statements ]: P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 + P310
[ Personal Protective Equipment ]: Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]: C:Corrosive;
[ Risk Phrases ]: R34;R37
[ Safety Phrases ]: S26-S45-S36/37/39-S9-S33-S29-S16-S46
[ RIDADR ]: UN 2924 3/PG 2
[ WGK Germany ]: 2
[ RTECS ]: MW4025000
[ Packaging Group ]: I
[ Hazard Class ]: 3
[ HS Code ]: 2806100000

 Customs

[ HS Code ]: 2806100000

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