m-PEG2-Tos structure
|
Common Name | m-PEG2-Tos | ||
|---|---|---|---|---|
| CAS Number | 50586-80-6 | Molecular Weight | 292.34900 | |
| Density | 1.179±0.06 g/cm3(Predicted) | Boiling Point | 392.3±27.0 °C(Predicted) | |
| Molecular Formula | C12H18O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of m-PEG2-Tosm-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Name | 2-(2-methoxyethoxy)ethanol,4-methylbenzenesulfonic acid |
|---|---|
| Synonym | More Synonyms |
| Description | m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| Density | 1.179±0.06 g/cm3(Predicted) |
|---|---|
| Boiling Point | 392.3±27.0 °C(Predicted) |
| Molecular Formula | C12H18O5S |
| Molecular Weight | 292.34900 |
| Exact Mass | 292.09800 |
| PSA | 101.44000 |
| LogP | 1.96420 |
|
~99%
m-PEG2-Tos CAS#:50586-80-6 |
| Literature: Harjani, Jitendra R.; Liang, Chen; Jessop, Philip G. Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1683 - 1691 |
|
~10%
m-PEG2-Tos CAS#:50586-80-6 |
| Literature: Hao, Jing; Servello, John; Sista, Prakash; Biewer, Michael C.; Stefan, Mihaela C. Journal of Materials Chemistry, 2011 , vol. 21, # 29 p. 10623 - 10628 |
|
~%
m-PEG2-Tos CAS#:50586-80-6 |
| Literature: Chao,Y. et al. Journal of the American Chemical Society, 1979 , vol. 101, # 17 p. 4948 - 4958 |
| Precursor 4 | |
|---|---|
| DownStream 10 | |
| diethylene glycol monomethyl ether-p-toluene sulfonate |
| diethyleneglycol monomethyl ether tosylate |