| Name | 1-Bromo-2-(2-methoxyethoxy)ethane |
|---|---|
| Synonyms |
1-Bromo-(2-methoxyethoxy)ethane
1-Bromo-2-(2-methoxyethoxy)ethane EINECS 259-000-6 MFCD00000238 1-(2-Bromoethoxy)-2-methoxyethane Ethane, 1-bromo-2-(2-methoxyethoxy)- Ethane, 1-(2-bromoethoxy)-2-methoxy- |
| Description | m-PEG2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 184.4±15.0 °C at 760 mmHg |
| Molecular Formula | C5H11BrO2 |
| Molecular Weight | 183.044 |
| Flash Point | 73.9±0.0 °C |
| Exact Mass | 181.994232 |
| PSA | 18.46000 |
| LogP | 0.54 |
| Vapour Pressure | 1.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.445 |
| Storage condition | Refrigerator (+4°C) |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | S24/25 |
| WGK Germany | 3 |
| HS Code | 2909199090 |
|
~91%
54149-17-6 |
| Literature: Wu, Zhongkui; Wu, Sanxie; Liang, Yingqiu Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2003 , vol. 59, # 7 p. 1631 - 1641 |
|
~97%
54149-17-6 |
| Literature: Northrop, Brian H.; Gloeckner, Andreas; Stang, Peter J. Journal of Organic Chemistry, 2008 , vol. 73, # 5 p. 1787 - 1794 |
| HS Code | 2909199090 |
|---|---|
| Summary | 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |