m-PEG2-amido-Ph-NH2

Modify Date: 2024-01-09 00:06:28

m-PEG2-amido-Ph-NH2 Structure
m-PEG2-amido-Ph-NH2 structure
Common Name m-PEG2-amido-Ph-NH2
CAS Number 1284417-66-8 Molecular Weight 238.28
Density N/A Boiling Point N/A
Molecular Formula C12H18N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG2-amido-Ph-NH2


m-PEG2-amido-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG2-amido-Ph-NH2

 m-PEG2-amido-Ph-NH2 Biological Activity

Description m-PEG2-amido-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H18N2O3
Molecular Weight 238.28
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