GSK3β inhibitor II
Modify Date: 2024-01-05 09:20:07
GSK3β inhibitor II structure
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Common Name | GSK3β inhibitor II | ||
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| CAS Number | 478482-75-6 | Molecular Weight | 395.21800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H10IN3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GSK3β inhibitor IIGSK3β inhibitor II is an inhibitor of GSK3β. GSK3β inhibitor II can be used for research of Alzheimer’s disease (AD)[1]. |
| Name | 2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole |
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| Synonym | More Synonyms |
| Description | GSK3β inhibitor II is an inhibitor of GSK3β. GSK3β inhibitor II can be used for research of Alzheimer’s disease (AD)[1]. |
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| Related Catalog | |
| Target |
GSK-3β |
| In Vitro | GSK3β inhibitor II 与 Ile62、Phe67、Val70、Ala83 和 Leu188 具有疏水相互作用，与 Lys85 具有离子相互作用，以及与 Lys85 和 Val135 残基具有氢键相互作用[1]。 GSK3β inhibitor II 与 Val135[1] 形成氢键。 |
| References |
| Molecular Formula | C14H10IN3OS |
|---|---|
| Molecular Weight | 395.21800 |
| Exact Mass | 394.95900 |
| PSA | 77.11000 |
| LogP | 4.02850 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Lo Monte, Fabio; Kramer, Thomas; Gu, Jiamin; Anumala, Upendra Rao; Marinelli, Luciana; La Pietra, Valeria; Novellino, Ettore; Franco, Benedicte; Demedts, David; Van Leuven, Fred; Fuertes, Ana; Dominguez, Juan Manuel; Plotkin, Batya; Eldar-Finkelman, Hagit; Schmidt, Boris Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4407 - 4424 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Narum, Lars; Norskov-Lauritsen, Leif; Olesen, Preben H. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 11 p. 1525 - 1528 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Lo Monte, Fabio; Kramer, Thomas; Gu, Jiamin; Anumala, Upendra Rao; Marinelli, Luciana; La Pietra, Valeria; Novellino, Ettore; Franco, Benedicte; Demedts, David; Van Leuven, Fred; Fuertes, Ana; Dominguez, Juan Manuel; Plotkin, Batya; Eldar-Finkelman, Hagit; Schmidt, Boris Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4407 - 4424 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Lo Monte, Fabio; Kramer, Thomas; Gu, Jiamin; Anumala, Upendra Rao; Marinelli, Luciana; La Pietra, Valeria; Novellino, Ettore; Franco, Benedicte; Demedts, David; Van Leuven, Fred; Fuertes, Ana; Dominguez, Juan Manuel; Plotkin, Batya; Eldar-Finkelman, Hagit; Schmidt, Boris Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4407 - 4424 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Lo Monte, Fabio; Kramer, Thomas; Gu, Jiamin; Anumala, Upendra Rao; Marinelli, Luciana; La Pietra, Valeria; Novellino, Ettore; Franco, Benedicte; Demedts, David; Van Leuven, Fred; Fuertes, Ana; Dominguez, Juan Manuel; Plotkin, Batya; Eldar-Finkelman, Hagit; Schmidt, Boris Journal of Medicinal Chemistry, 2012 , vol. 55, # 9 p. 4407 - 4424 |
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GSK3β inhibitor II CAS#:478482-75-6 |
| Literature: Lukas, Thomas J.; Schiltz, Gary E.; Arrat, Hasan; Scheidt, Karl; Siddique, Teepu Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 6 p. 1532 - 1537 |
| GSK-3b Inhibitor II |
| Glycogen Synthase Kinase-3beta Inhibitor II |
| GSK-3 Inhibitor II |
| GSK-3beta Inhibitor II |
| 2-(3-iodobenzylthio)-5-(pyridin-4-yl)-1,3,4-oxadiazole |
| 2-thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]oxadiazole |
| HMS3229G14 |