203915-59-7

203915-59-7 structure

Name: MMP Inhibitor II
Chemical Name: N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl-1,3-diazinane-2-carboxamide
CAS Number: 203915-59-7
Molecular Formula: C₂₁H₂₇N₃O₈S₂
Molecular Weight: 513.584
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2017-09-16 14:06:13
Modify Date: 2024-01-13 17:29:31
MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively[1].

Name	N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl-1,3-diazinane-2-carboxamide
Synonyms	N25 2-Pyrimidinecarboxamide, hexahydro-N-hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethyl- N-Hydroxy-1,3-bis[(4-methoxyphenyl)sulfonyl]-5,5-dimethylhexahydro-2-pyrimidinecarboxamide 1bqo mmp inhibitor ii

Description	MMP Inhibitor II (compound 4e) is a potent, reversible pan-MMP inhibitor with IC50 values of 24 nM, 18.4 nM, 30 nM, and 2.7 nM for MMP-1,MMP-3, MMP-7, and MMP-9, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP-1:24 nM (IC50) MMP-3:18.4 nM (IC50) MMP-7:30 nM (IC50) MMP-9:2.7 nM (IC50)
References	[1]. S Pikul, et al. Discovery of potent, achiral matrix metalloproteinase inhibitors. J Med Chem. 1998 Sep 10;41(19):3568-71.