BAY-4931
Modify Date: 2025-10-30 01:11:12
BAY-4931 structure
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Common Name | BAY-4931 | ||
|---|---|---|---|---|
| CAS Number | 423150-91-8 | Molecular Weight | 421.83 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H16ClN3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAY-4931BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC50 of 0.17 nM[1]. |
| Name | BAY-4931 |
|---|
| Description | BAY-4931 is a potent, covalent and selective PPARγ inverse-agonist with an IC50 of 0.17 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
PPAR-γ:0.17 nM (IC50, RT112-FABP4-NLucP cellular reporter assay) mouse PPARγ:0.14 nM (IC50, GAL4-NHR-LBD one hybrid reporter assay ) hPPARγ:0.40 nM (IC50, GAL4-NHR-LBD one hybrid reporter assay ) |
| In Vitro | BAY-4931 (0-10 μM; 7 days) inhibits UM-UC-9 proliferation with an IC50 of 3.4 nM[1]. BAY-4931 only inhibits CYP2C8 in CYP inhibition test[1]. Cell Proliferation Assay[1] Cell Line: UM-UC-9 cells Concentration: 0-10 μM Incubation Time: 7 days Result: Inhibited proliferation with an IC50 of 3.4 nM. |
| Molecular Formula | C22H16ClN3O4 |
|---|---|
| Molecular Weight | 421.83 |
| InChIKey | WFEBALYYDASKIV-UHFFFAOYSA-N |
| SMILES | CCc1ccc(-c2nc3cc(NC(=O)c4cc([N+](=O)[O-])ccc4Cl)ccc3o2)cc1 |