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1799759-24-2

1799759-24-2 structure
1799759-24-2 structure
  • Name: BAY-588
  • Chemical Name: BAY-588
  • CAS Number: 1799759-24-2
  • Molecular Formula: C27H25F4N5O2
  • Molecular Weight: 527.51
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2021-01-10 00:37:29
  • Modify Date: 2024-01-28 22:51:57
  • BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM[1].

Name BAY-588
Synonyms BAY-588
2,4-Quinolinedicarboxamide, N4-[1-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-
7-Fluoro-N4-{5-methyl-1-[4-(2-methyl-2-propanyl)benzyl]-3-(trifluoromethyl)-1H-pyrazol-4-yl}-2,4-quinolinedicarboxamide
N4-[1-[[4-(1,1-Dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide
Description BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM[1].
Related Catalog
Target

IC50=1.18μM(GLUT1)[1], IC50>10μM(GLUT2)[1], IC50=5.47μM(GLUT3)[1], IC50=0.5μM(GLUT4)[1]

References

[1]. Holger Siebeneicher, et, al. Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem. 2016, 11, 20.  

Density 1.4±0.1 g/cm3
Boiling Point 603.7±55.0 °C at 760 mmHg
Molecular Formula C27H25F4N5O2
Molecular Weight 527.51
Flash Point 318.9±31.5 °C
Exact Mass 527.194458
LogP 6.14
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.604
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