Mycobactin-IN-2

Modify Date: 2024-01-10 20:33:33

Mycobactin-IN-2 Structure
Mycobactin-IN-2 structure
Common Name Mycobactin-IN-2
CAS Number 421573-09-3 Molecular Weight 317.18
Density N/A Boiling Point N/A
Molecular Formula C15H13BrN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mycobactin-IN-2


Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].

 Names

Name Mycobactin-IN-2

 Mycobactin-IN-2 Biological Activity

Description Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].
Related Catalog
Target

Mycobactin[1]

In Vitro Mycobactin-IN-2 exhibits notable activity against M. tuberculosis in iron-impoverished media with MIC90 8 μg/mL[1].
References

[1]. Shyam M, et, al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition. J Med Chem. 2022 Jan 13;65(1):234-256.

 Chemical & Physical Properties

Molecular Formula C15H13BrN2O
Molecular Weight 317.18
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