421573-09-3

421573-09-3 structure
421573-09-3 structure
  • Name: Mycobactin-IN-2
  • Chemical Name: Mycobactin-IN-2
  • CAS Number: 421573-09-3
  • Molecular Formula: C15H13BrN2O
  • Molecular Weight: 317.18
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-04-15 18:00:31
  • Modify Date: 2024-01-10 20:33:33
  • Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].

Name Mycobactin-IN-2
Description Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].
Related Catalog
Target

Mycobactin[1]

In Vitro Mycobactin-IN-2 exhibits notable activity against M. tuberculosis in iron-impoverished media with MIC90 8 μg/mL[1].
References

[1]. Shyam M, et, al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition. J Med Chem. 2022 Jan 13;65(1):234-256.

Molecular Formula C15H13BrN2O
Molecular Weight 317.18