(R)-Verapamil hydrochloride

Modify Date: 2024-01-16 13:19:23

(R)-Verapamil hydrochloride structure	Common Name	(R)-Verapamil hydrochloride
	CAS Number	38176-02-2	Molecular Weight	477.03600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₉ClN₂O₄	Melting Point	129-131℃
	MSDS	Chinese USA	Flash Point	N/A

Use of (R)-Verapamil hydrochloride

(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer drugs[1][2].

Name	R(+)-Verapamil monohydrochloride hydrate
Synonym	More Synonyms

Description	(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer drugs[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
References	[1]. Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92. [2]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

References

[1]. Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92.

[2]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22.

Melting Point	129-131℃
Molecular Formula	C₂₇H₃₉ClN₂O₄
Molecular Weight	477.03600
Exact Mass	476.24400
PSA	65.15000
LogP	0.43398

(R)-Verapamil hydrochloride MSDS(Chinese)

Hazard Codes	T: Toxic;
Risk Phrases	23/24/25
Safety Phrases	22-36/37/39-45
RIDADR	UN 2811 6.1/PG 3

(+)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl](5,6-dimethoxyphenethyl)methylammonium chloride

DC Chemicals Limited
China
Product Name: (R)-Verapamil hydrochloride
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (+)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl](5,6-dimethoxyphenethyl)methylammonium chloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

(R)-Verapamil hydrochloride suppliers

(R)-Verapamil hydrochloride price

(R)-Verapamil hydrochloride

Use of (R)-Verapamil hydrochloride

Names

(R)-Verapamil hydrochloride Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Synonyms