(S)-Verapamil hydrochloride

Modify Date: 2024-01-05 11:30:15

(S)-Verapamil hydrochloride structure	Common Name	(S)-Verapamil hydrochloride
	CAS Number	36622-28-3	Molecular Weight	491.06300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₃₉ClN₂O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of (S)-Verapamil hydrochloride

(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1].

Name	S(−)-Verapamil hydrochloride hydrate
Synonym	More Synonyms

Description	(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor
Target	LTC4 Ca2+
In Vitro	(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) not the (R)-Verapamil hydrochloride potently induces the death of MRP1-transfected BHK-21 cells[1]. (S)-Verapamil hydrochloride is good active form and has the low bioavailability[1].
References	[1]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22. [2]. Tannergren C, et al. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther. 2004 Apr;75(4):298-309.

Molecular Formula	C₂₇H₃₉ClN₂O₄
Molecular Weight	491.06300
Exact Mass	490.26000
PSA	63.95000
LogP	5.89508

(S)-Verapamil hydrochloride MSDS(Chinese)

RIDADR	UN 2811 6.1/PG 3

2-(3,4-dimethoxyphenyl)-2-propan-2-ylpentanedinitrile structure

2-(3,4-dimethox...

CAS#:102201-30-9

~%

(S)-Verapamil hydrochloride Structure

(S)-Verapamil h...

CAS#:36622-28-3

Literature: Organic Process Research and Development, , vol. 4, # 6 p. 467 - 472

4-cyano-4-(3,4-dimethoxyphenyl)-5-methyl hexanoic acid structure

4-cyano-4-(3,4-...

CAS#:36622-23-8

~%

(S)-Verapamil hydrochloride Structure

(S)-Verapamil h...

CAS#:36622-28-3

Literature: Organic Process Research and Development, , vol. 4, # 6 p. 467 - 472

UNII:1Z42YUG42K structure

UNII:1Z42YUG42K

CAS#:20850-49-1

~%

(S)-Verapamil hydrochloride Structure

(S)-Verapamil h...

CAS#:36622-28-3

Literature: Organic Process Research and Development, , vol. 4, # 6 p. 467 - 472

Precursor 3
CAS#:102201-30-9 2-(3,4-dimethox... CAS#:36622-23-8 4-cyano-4-(3,4-... CAS#:20850-49-1 UNII:1Z42YUG42K
DownStream 0

s(-)-verapamil

MFCD00069355

EINECS 253-132-8

DC Chemicals Limited
China
Product Name: (S)-Verapamil hydrochloride
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (S)-(-)-VERAPAMIL HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

(S)-Verapamil hydrochloride suppliers

(S)-Verapamil hydrochloride price