CYR-101
Modify Date: 2024-01-09 17:26:58
CYR-101 structure
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Common Name | CYR-101 | ||
|---|---|---|---|---|
| CAS Number | 359625-79-9 | Molecular Weight | 366.429 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 551.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C22H23FN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 287.4±30.1 °C | |
Use of CYR-101MIN-101 is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively). |
| Name | 2-[[1-[2-(4-fluorophenyl)-2-oxoethyl]piperidin-4-yl]methyl]-3H-isoindol-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | MIN-101 is a novel cyclic amide derivative that has high equipotent affinities for 5-HT2A and sigma-2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A and sigma-2, respectively). |
|---|---|
| Related Catalog | |
| Target |
Ki: 7.53 nM (5-HT2A), 8.19 nM (sigma-2)[1] |
| In Vitro | MIN-101 also shows binding affinity for α1-adrenergic receptors but low or no affinity for muscarinic, cholinergic, and histaminergic receptors. Although MIN-101 has no affinities for pre- or postsynaptic dopaminergic receptors, it is probable that sigma-2 receptors are implicated in the modulation of dopamine and glutamatergic pathways, as well as in calcium neuronal modulation[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 551.7±50.0 °C at 760 mmHg |
| Molecular Formula | C22H23FN2O2 |
| Molecular Weight | 366.429 |
| Flash Point | 287.4±30.1 °C |
| Exact Mass | 366.174347 |
| PSA | 40.62000 |
| LogP | 2.59 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.593 |
| unii-4p31i0m3bf |
| 1H-Isoindol-1-one, 2-[[1-[2-(4-fluorophenyl)-2-oxoethyl]-4-piperidinyl]methyl]-2,3-dihydro- |
| 2-({1-[2-(4-Fluorophenyl)-2-oxoethyl]-4-piperidinyl}methyl)-1-isoindolinone |
| CYR-101 |