2219362-20-4
2219362-20-4 structure
- Name: SPX-101
- Chemical Name: SPX-101
- CAS Number: 2219362-20-4
- Molecular Formula: C53H90N14O16
- Molecular Weight: 1179.385
- Create Date: 2020-01-11 15:13:51
- Modify Date: 2024-04-05 16:06:34
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SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits; promotes durable reduction of ENaC membrane concentration, increases mucus transport in the β-ENaC mouse model as well as the sheep model of CF. Fibrosis Phase 2 Clinical
| Name | SPX-101 |
|---|
| Description | SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits; promotes durable reduction of ENaC membrane concentration, increases mucus transport in the β-ENaC mouse model as well as the sheep model of CF. Fibrosis Phase 2 Clinical |
|---|---|
| References | References 1. Scott DW, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):734-744. 2. Lennox A, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):671-672. View Related Products by Target Sodium Channel Fibrosis |
| Molecular Formula | C53H90N14O16 |
|---|---|
| Molecular Weight | 1179.385 |