Etiracetam

Modify Date: 2024-01-02 23:19:35

Etiracetam Structure
Etiracetam structure
Common Name Etiracetam
CAS Number 33996-58-6 Molecular Weight 170.209
Density 1.2±0.1 g/cm3 Boiling Point 395.9±25.0 °C at 760 mmHg
Molecular Formula C8H14N2O2 Melting Point N/A
MSDS N/A Flash Point 193.2±23.2 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of Etiracetam


Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059)[1].

 Names

Name 2-(2-oxopyrrolidin-1-yl)butanamide
Synonym More Synonyms

 Etiracetam Biological Activity

Description Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059)[1].
Related Catalog
Target

Acetylcholine[1].

References

[1]. Hovinga CA, et al. Levetiracetam: a novel antiepileptic drug. Pharmacotherapy. 2001 Nov;21(11):1375-88.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 395.9±25.0 °C at 760 mmHg
Molecular Formula C8H14N2O2
Molecular Weight 170.209
Flash Point 193.2±23.2 °C
Exact Mass 170.105530
PSA 64.39000
LogP -0.67
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.519
Storage condition 2-8℃

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H319-H411
Precautionary Statements P273-P305 + P351 + P338
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36
Safety Phrases S26
RIDADR UN 3077 9 / PGIII

 Articles27

More Articles
Inhibition of excitatory synaptic transmission in hippocampal neurons by levetiracetam involves Zn²⁺-dependent GABA type A receptor-mediated presynaptic modulation.

J. Pharmacol. Exp. Ther. 348(2) , 246-59, (2014)

Levetiracetam (LEV) is an antiepileptic drug with a unique but as yet not fully resolved mechanism of action. Therefore, by use of a simplified rat-isolated nerve-bouton preparation, we have investiga...

Efficacy and safety of pregabalin versus levetiracetam as adjunctive therapy in patients with partial seizures: a randomized, double-blind, noninferiority trial.

Epilepsia 55(7) , 1048-57, (2014)

To assess the comparative efficacy and safety of pregabalin and levetiracetam for the reduction of seizure frequency in patients with partial seizures.This was a randomized, double-blind, flexible-dos...

The established status epilepticus trial 2013.

Epilepsia 54 Suppl 6 , 89-92, (2013)

Benzodiazepine-refractory status epilepticus (established status epilepticus, ESE) is a relatively common emergency condition with several widely used treatments. There are no controlled, randomized, ...

 Synonyms

1-Pyrrolidineacetamide, α-ethyl-2-oxo-
UCB 6474
(±)-a-Ethyl-2-oxo-1-pyrrolidineacetamide
ucb L059
T5NVTJ AY2&VZ
Etiracetam
2-(2-Oxo-1-pyrrolidinyl)butanamide
α-Ethyl-2-oxo-1-pyrrolidineacetamide
UNII:230447L0GL
Levetiracetam Racemic Mixture
乙拉西坦
2-(2-Oxopyrrolidin-1-yl)butyramide
(±)-α-Ethyl-2-oxo-1-pyrrolidineacetamide
2-(2-oxopyrrolidin-1-yl)butanamide
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Price: ¥660/10 mM * 1 mL in DMSO

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