Etiracetam
Names
[ CAS No. ]:
33996-58-6
[ Name ]:
Etiracetam
[Synonym ]:
1-Pyrrolidineacetamide, α-ethyl-2-oxo-
UCB 6474
(±)-a-Ethyl-2-oxo-1-pyrrolidineacetamide
ucb L059
T5NVTJ AY2&VZ
Etiracetam
2-(2-Oxo-1-pyrrolidinyl)butanamide
α-Ethyl-2-oxo-1-pyrrolidineacetamide
UNII:230447L0GL
Levetiracetam Racemic Mixture
乙拉西坦
2-(2-Oxopyrrolidin-1-yl)butyramide
(±)-α-Ethyl-2-oxo-1-pyrrolidineacetamide
2-(2-oxopyrrolidin-1-yl)butanamide
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Acetylcholine[1].
[References]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
395.9±25.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H14N2O2
[ Molecular Weight ]:
170.209
[ Flash Point ]:
193.2±23.2 °C
[ Exact Mass ]:
170.105530
[ PSA ]:
64.39000
[ LogP ]:
-0.67
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.519
[ Storage condition ]:
2-8℃
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H319-H411
[ Precautionary Statements ]:
P273-P305 + P351 + P338
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36
[ Safety Phrases ]:
S26
[ RIDADR ]:
UN 3077 9 / PGIII
Articles
J. Pharmacol. Exp. Ther. 348(2) , 246-59, (2014)
Levetiracetam (LEV) is an antiepileptic drug with a unique but as yet not fully resolved mechanism of action. Therefore, by use of a simplified rat-isolated nerve-bouton preparation, we have investiga...
Efficacy and safety of pregabalin versus levetiracetam as adjunctive therapy in patients with partial seizures: a randomized, double-blind, noninferiority trial.Epilepsia 55(7) , 1048-57, (2014)
To assess the comparative efficacy and safety of pregabalin and levetiracetam for the reduction of seizure frequency in patients with partial seizures.This was a randomized, double-blind, flexible-dos...
The established status epilepticus trial 2013.Epilepsia 54 Suppl 6 , 89-92, (2013)
Benzodiazepine-refractory status epilepticus (established status epilepticus, ESE) is a relatively common emergency condition with several widely used treatments. There are no controlled, randomized, ...