Col 003

Modify Date: 2025-08-27 15:53:29

Col 003 Structure
Col 003 structure
 Common Name Col 003
CAS Number 328565-16-8 Molecular Weight 257.24
Density N/A Boiling Point N/A
Molecular Formula C14H11NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Col 003


Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].

 Names

Name Col003

 Col 003 Biological Activity

Description Col003 is a potent inhibitor of Hsp47, competitively binds to the collagen binding site on Hsp47 (IC50, 1.8 μM), and inhibits collagen secretion by destabilizing the collagen triple helix[1].
Related Catalog
Target

HSP47:1.8 μM (IC50)

References

[1]. Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.

 Chemical & Physical Properties

Molecular Formula C14H11NO4
Molecular Weight 257.24
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Chemsrc provides Col 003(CAS#:328565-16-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Col 003 are included as well.>> amp version: Col 003

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