Apigenin-7-glucuronide

Modify Date: 2024-01-03 17:07:51

Apigenin-7-glucuronide structure	Common Name	Apigenin-7-glucuronide
	CAS Number	29741-09-1	Molecular Weight	446.361
	Density	1.7±0.1 g/cm3	Boiling Point	841.8±65.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₁₈O₁₁	Melting Point	>300℃
	MSDS	Chinese USA	Flash Point	299.0±27.8 °C
	Symbol	GHS07	Signal Word	Warning

Use of Apigenin-7-glucuronide

Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively.

Name	Apigenin 7-glucuronide
Synonym	More Synonyms

Description	Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively.
Related Catalog	Research Areas >> Cancer Natural Products >> Flavonoids
Target	MMP-3:12.87 μM (IC50) MMP-8:22.39 μM (IC50) MMP-9:17.52 μM (IC50) MMP13:0.27 μM (IC50)
In Vitro	Apigenin-7-Oglucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Scutellarin A also inhibits the migrated capacity of ACHN and 786-O cells in a dose-dependent manner. It is also revealed that after treatment with Scutellarin A (30, 60, and 90 μM) for 24 h, the apoptosis rates in ACHN and 786-O cells are remarkably enhanced dose-dependently when compared to the control groups[2].
References	[1]. Crascì L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911. [2]. Deng W, et al. Scutellarin inhibits human renal cancer cell proliferation and migration via upregulation of PTEN. Biomed Pharmacother. 2018 Nov;107:1505-1513.

Density	1.7±0.1 g/cm3
Boiling Point	841.8±65.0 °C at 760 mmHg
Melting Point	>300℃
Molecular Formula	C₂₁H₁₈O₁₁
Molecular Weight	446.361
Flash Point	299.0±27.8 °C
Exact Mass	446.084900
PSA	187.12000
LogP	-0.55
Vapour Pressure	0.0±3.3 mmHg at 25°C
Index of Refraction	1.740
Storage condition	?20°C

Apigenin-7-glucuronide MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
Risk Phrases	22
RIDADR	NONH for all modes of transport

Apigenin structure

Apigenin

CAS#:520-36-5

(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic structure

(2S,3S,4R,5R,6R...

CAS#:2616-64-0

~%

Apigenin-7-glucuronide Structure

Apigenin-7-gluc...

CAS#:29741-09-1

Literature: Phytochemistry, , vol. 71, # 7 p. 726 - 735

Precursor 2
CAS#:520-36-5 Apigenin CAS#:2616-64-0 (2S,3S,4R,5R,6R...
DownStream 2
CAS#:6556-12-3 α-D-Glucopyranu... CAS#:520-36-5 Apigenin

Apigenin 7-O-glucuronide

5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl β-D-glucopyranosiduronic acid

(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranuronosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Apigenin-7-glucuronide
Price: ￥888.0/5mg ￥1148.0/10mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Apigenin-7-O-glucuronide
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: APIGENIN 7-O-B-GLUCURONIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥1248/5mg

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