Topoisomerase II inhibitor 7

Modify Date: 2025-10-12 02:05:58

Topoisomerase II inhibitor 7 structure	Common Name	Topoisomerase II inhibitor 7
	CAS Number	2697171-03-0	Molecular Weight	674.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₂₈BrN₅O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Topoisomerase II inhibitor 7

Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].

Name	Topoisomerase II inhibitor 7

Description	Topoisomerase II inhibitor 7 (compound 3a) is a potent inhibitor of topoisomerase II alpha subtype, with an IC50 of 3.19 μM. Topoisomerase II inhibitor 7 can induce cell cycle arrest and apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	topoisomerase II alpha:3.19 μM (IC50)
References	[1]. Nemr MTM, et, al. Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity. Bioorg Chem. 2020 Dec;105:104446.

Molecular Formula	C₃₂H₂₈BrN₅O₅S
Molecular Weight	674.56

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