2493298-68-1

2493298-68-1 structure

Name: Topoisomerase II inhibitor 8
Chemical Name: Topoisomerase II inhibitor 8
CAS Number: 2493298-68-1
Molecular Formula: C₁₄H₈N₄O₃S
Molecular Weight: 312.30
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2022-08-17 18:20:12
Modify Date: 2024-01-12 12:37:45
Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].

Name	Topoisomerase II inhibitor 8

Description	Topoisomerase II inhibitor 8 (compound 22) is a potent topoisomerase II inhibitor, with an IC50 of 0.52 μM. Topoisomerase II inhibitor 8 exhibits good anti-proliferative activities and can arrest the cell cycle at G2/M phase[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	Topoisomerase II:0.52 μM (IC50)
References	[1]. Abbass EM, et, al. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers. Bioorg Chem. 2020 Nov;104:104255.

Molecular Formula	C₁₄H₈N₄O₃S
Molecular Weight	312.30