Topoisomerase II inhibitor 10

Modify Date: 2025-10-25 16:30:30

Topoisomerase II inhibitor 10 Structure
Topoisomerase II inhibitor 10 structure
 Common Name Topoisomerase II inhibitor 10
CAS Number 2488208-96-2 Molecular Weight 572.55
Density N/A Boiling Point N/A
Molecular Formula C27H20N6O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Topoisomerase II inhibitor 10


Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells[1].

 Names

Name Topoisomerase II inhibitor 10

 Topoisomerase II inhibitor 10 Biological Activity

Description Topoisomerase II inhibitor 10 (compound 32a) is a potent topoisomerase II inhibitor with an IC50 value of 7.45 μM. Topoisomerase II inhibitor 10 causes cell cycle arrest at G2-M phase and induces apoptosis of HepG-2 cells. Topoisomerase II inhibitor 10 has excellent anti-proliferative activities against HepG-2, MCF-7, and HCT-116 cells[1].
Related Catalog
Target

Topoisomerase II:7.45 μM (IC50)

References

[1]. El-Helby AA, et al. Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors. Bioorg Chem. 2020 Oct;103:104233.

 Chemical & Physical Properties

Molecular Formula C27H20N6O7S
Molecular Weight 572.55
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Chemsrc provides Topoisomerase II inhibitor 10(CAS#:2488208-96-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Topoisomerase II inhibitor 10 are included as well.>> amp version: Topoisomerase II inhibitor 10

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