Boc-NH-PEG1-OH structure
|
Common Name | Boc-NH-PEG1-OH | ||
|---|---|---|---|---|
| CAS Number | 26690-80-2 | Molecular Weight | 161.199 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 267.2±23.0 °C at 760 mmHg | |
| Molecular Formula | C7H15NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 115.4±22.6 °C | |
| Symbol |
GHS05, GHS06 |
Signal Word | Danger | |
Use of Boc-NH-PEG1-OHBoc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | tert-butyl n-(2-hydroxyethyl)carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 267.2±23.0 °C at 760 mmHg |
| Molecular Formula | C7H15NO3 |
| Molecular Weight | 161.199 |
| Flash Point | 115.4±22.6 °C |
| Exact Mass | 161.105194 |
| PSA | 58.56000 |
| LogP | 0.49 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.450 |
| Storage condition | 2-8°C |
| Symbol |
GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H315-H318-H335 |
| Precautionary Statements | P261-P280-P301 + P310-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic; |
| Risk Phrases | R25;R37/38;R41 |
| Safety Phrases | S26-S39-S45-S36/37/39 |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| Hazard Class | 6.1 |
| HS Code | 2924199090 |
| Precursor 10 | |
|---|---|
| DownStream 10 | |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synthesis , 133, (1993)
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Synth. Commun. 21 , 359, (1991)
|
| tert-Butyl (2-hydroxyethyl)carbamate |
| (2-hydroxyethyl)carbamic acid t-butyl ester |
| Boc-NH-(CH2)2-1-naphthylamide |
| boc-ethanolamine |
| Boc-2-aminoethanol |
| 2-Boc-ethanolamine |
| 2-(tert-Butoxycarbonyl)ethanolamine |
| 2-(tert-ButoxycarbonylaMino)-1-ethanol |
| (2-hydroxy-ethyl)-carbamic acid tert-butyl ester |
| Carbamic acid, N-(2-hydroxyethyl)-, 1,1-dimethylethyl ester |
| MFCD00056657 |
| N-(t-butoxycarbonyl)-2-hydroxy-ethylamine |
| N-(tert-Butoxycarbonyl)ethanolamine |
| 2-(Boc-amino)-1-ethanol |
| N-(2-Hydroxyethyl)carbamic Acid tert-Butyl Ester |
| boc-aminoethanol |
| Boc-Gly-ol |
| Boc-glycinol |
| 2-Methyl-2-propanyl (2-hydroxyethyl)carbamate |
| N-Boc-ethanolamine |
| tert-Butyl N-(2-Hydroxyethyl)carbamate |
| 2-(tert-butoxycarbonylamino)ethanol |
| tert-butyl N-(2-hydroxyethyl)-carbamate |