Boc-NH-PEG12-CH2CH2COOH

Modify Date: 2024-01-09 19:33:11

Boc-NH-PEG12-CH2CH2COOH Structure
Boc-NH-PEG12-CH2CH2COOH structure
Common Name Boc-NH-PEG12-CH2CH2COOH
CAS Number 1415981-79-1 Molecular Weight 717.840
Density 1.1±0.1 g/cm3 Boiling Point 736.3±60.0 °C at 760 mmHg
Molecular Formula C32H63NO16 Melting Point N/A
MSDS N/A Flash Point 399.1±32.9 °C

 Use of Boc-NH-PEG12-CH2CH2COOH


Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35,38,41-tridecaoxa-5-azatetratetracontan-44-oic acid
Synonym More Synonyms

 Boc-NH-PEG12-CH2CH2COOH Biological Activity

Description Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 736.3±60.0 °C at 760 mmHg
Molecular Formula C32H63NO16
Molecular Weight 717.840
Flash Point 399.1±32.9 °C
Exact Mass 717.414673
LogP -3.01
Vapour Pressure 0.0±5.2 mmHg at 25°C
Index of Refraction 1.469

 Safety Information

Hazard Codes Xi

 Synonyms

3,8,11,14,17,20,23,26,29,32,35,38,41-Tridecaoxa-5-azatetratetracontan-44-oic acid, 2,2-dimethyl-4-oxo-
MFCD13185149
2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29,32,35,38,41-tridecaoxa-5-azatetratetracontan-44-oic acid