1642551-09-4

1642551-09-4 structure

1642551-09-4 structure

Name: Bocnh-peg12-ch2ch2nh2
Chemical Name: Boc-NH-PEG12-NH2
CAS Number: 1642551-09-4
Molecular Formula: C₃₁H₆₄N₂O₁₄
Molecular Weight: 688.84
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:33:29
Modify Date: 2024-04-04 20:22:09
Boc-NH-PEG12-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Boc-NH-PEG12-NH2

Description	Boc-NH-PEG12-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₁H₆₄N₂O₁₄
Molecular Weight	688.84