BTK-IN-23
Modify Date: 2024-04-08 18:42:45
BTK-IN-23 structure
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Common Name | BTK-IN-23 | ||
|---|---|---|---|---|
| CAS Number | 2573048-11-8 | Molecular Weight | 468.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H28N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BTK-IN-23BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]. |
| Name | BTK-IN-23 |
|---|
| Description | BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]. |
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| Related Catalog | |
| In Vitro | BTK-IN-23 (化合物 3) 抑制 Jeko-1 细胞中的 BTK 自磷酸化，IC50 为 314 nM[1]。 Western Blot Analysis[1] Cell Line: Jeko-1 cell Concentration: 0.01, 0.1, 1, 10 μM Incubation Time: 2 h Result: Inhibited BTK autophosphorylation. |
| References |
| Molecular Formula | C27H28N6O2 |
|---|---|
| Molecular Weight | 468.55 |