2361192-21-2

2361192-21-2 structure

Name: BTK-IN-9
Chemical Name: BTK-IN-9
CAS Number: 2361192-21-2
Molecular Formula: C₂₅H₁₉N₇O₄
Molecular Weight: 481.46
Create Date: 2022-06-16 18:17:08
Modify Date: 2025-08-25 17:42:35
BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells[1].

Name	BTK-IN-9

Description	BTK-IN-9 is a reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. BTK-IN-9 specifically disturbs mitochondrial membrane potential and increases reactive oxygen species level in Z138 cells. BTK-IN-9 also induces cell apoptosis in Z138 cells[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References	[1]. Ran F, et al. Design and synthesis of novel pyrazolopyrimidine-based derivatives as reversible BTK inhibitors with potent antiproliferative activity in mantle cell lymphoma. Med Chem Res, 2022, 31, 594-604.

Molecular Formula	C₂₅H₁₉N₇O₄
Molecular Weight	481.46