2573048-11-8
2573048-11-8 structure
- Name: BTK-IN-23
- Chemical Name: BTK-IN-23
- CAS Number: 2573048-11-8
- Molecular Formula: C27H28N6O2
- Molecular Weight: 468.55
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Btk
- Create Date: 2023-04-05 10:52:38
- Modify Date: 2024-04-08 18:42:45
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BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1].
| Name | BTK-IN-23 |
|---|
| Description | BTK-IN-23 is a BTK inhibitor (IC50: 12.8 nM). BTK-IN-23 also inhibits BLX and BMX with IC50s of 35.6 and 5.7 nM respectively. BTK-IN-23 shows improved kinase selectivity compared to Ibrutinib (HY-10997)[1]. |
|---|---|
| Related Catalog | |
| In Vitro | BTK-IN-23 (化合物 3) 抑制 Jeko-1 细胞中的 BTK 自磷酸化，IC50 为 314 nM[1]。 Western Blot Analysis[1] Cell Line: Jeko-1 cell Concentration: 0.01, 0.1, 1, 10 μM Incubation Time: 2 h Result: Inhibited BTK autophosphorylation. |
| References |
| Molecular Formula | C27H28N6O2 |
|---|---|
| Molecular Weight | 468.55 |