Keap1-Nrf2-IN-10

Modify Date: 2025-08-24 11:53:53

Keap1-Nrf2-IN-10 structure	Common Name	Keap1-Nrf2-IN-10
	CAS Number	2445349-54-0	Molecular Weight	808.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₂I₂N₄O₇S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Keap1-Nrf2-IN-10

Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].

Name	Keap1-Nrf2-IN-10

Description	Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	NQO1[1]
References	[1]. Soliman AM, et al. Radiomodulatory effect of a non-electrophilic NQO1 inducer identified in a screen of new 6, 8-diiodoquinazolin-4(3H)-ones carrying a sulfonamide moiety. Eur J Med Chem. 2020 Aug 15;200:112467.

Molecular Formula	C₂₅H₂₂I₂N₄O₇S₂
Molecular Weight	808.40
InChIKey	AHGRGGWBXKWJMR-UHFFFAOYSA-N
SMILES	COc1cc(NC(=O)CSc2nc3c(I)cc(I)cc3c(=O)n2-c2ccc(S(N)(=O)=O)cc2)cc(OC)c1OC

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Keap1-Nrf2-IN-10

Use of Keap1-Nrf2-IN-10

Names

Keap1-Nrf2-IN-10 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.