Keap1-Nrf2-IN-10

Modify Date: 2025-08-24 11:53:53

Keap1-Nrf2-IN-10 Structure
Keap1-Nrf2-IN-10 structure
Common Name Keap1-Nrf2-IN-10
CAS Number 2445349-54-0 Molecular Weight 808.40
Density N/A Boiling Point N/A
Molecular Formula C25H22I2N4O7S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Keap1-Nrf2-IN-10


Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].

 Names

Name Keap1-Nrf2-IN-10

 Keap1-Nrf2-IN-10 Biological Activity

Description Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].
Related Catalog
Target

NQO1[1]

References

[1]. Soliman AM, et al. Radiomodulatory effect of a non-electrophilic NQO1 inducer identified in a screen of new 6, 8-diiodoquinazolin-4(3H)-ones carrying a sulfonamide moiety. Eur J Med Chem. 2020 Aug 15;200:112467.

 Chemical & Physical Properties

Molecular Formula C25H22I2N4O7S2
Molecular Weight 808.40
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.