HDAC6-AR-IN-10
Modify Date: 2024-04-12 09:33:30
HDAC6-AR-IN-10 structure
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Common Name | HDAC6-AR-IN-10 | ||
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| CAS Number | 2042519-10-6 | Molecular Weight | 579.571 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H25F4N5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HDAC6-AR-IN-10HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM); inhibits AR signaling and reduces the AR protein levels in LNCaP cells; a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6. |
| Name | HDAC6-AR-IN-10 |
|---|
| Description | HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM); inhibits AR signaling and reduces the AR protein levels in LNCaP cells; a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6. |
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| References | References 1. Jadhavar PS, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. View Related Products by Target HDAC |
| Molecular Formula | C26H25F4N5O4S |
|---|---|
| Molecular Weight | 579.571 |