HDAC6-AR-IN-10

Names

[ CAS No. ]:
2042519-10-6

[ Name ]:
HDAC6-AR-IN-10

Biological Activity

[Description]:

HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM); inhibits AR signaling and reduces the AR protein levels in LNCaP cells; a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6.

[References]

References 1. Jadhavar PS, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. View Related Products by Target HDAC

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₅F₄N₅O₄S

[ Molecular Weight ]:
579.571

Related Compounds

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