2042519-10-6
2042519-10-6 structure
- Name: HDAC6-AR-IN-10
- Chemical Name: HDAC6-AR-IN-10
- CAS Number: 2042519-10-6
- Molecular Formula: C26H25F4N5O4S
- Molecular Weight: 579.571
- Create Date: 2020-01-12 11:30:50
- Modify Date: 2024-04-12 09:33:30
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HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM); inhibits AR signaling and reduces the AR protein levels in LNCaP cells; a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6.
| Name | HDAC6-AR-IN-10 |
|---|
| Description | HDAC6-AR-IN-10 is a potent dual HDAC6/AR inhibitor with IC50 of 35.6 nM/<30 nM, shows weak inhibition on HDAC1/2/3 (IC50>1 uM); inhibits AR signaling and reduces the AR protein levels in LNCaP cells; a useful tool compound in pharmacology studies to evaluate the value of dual inhibition of AR and HDAC6. |
|---|---|
| References | References 1. Jadhavar PS, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5222-5228. View Related Products by Target HDAC |
| Molecular Formula | C26H25F4N5O4S |
|---|---|
| Molecular Weight | 579.571 |