InhA-IN-2

Modify Date: 2024-01-10 10:42:12

Use of InhA-IN-2

InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM[1].

Name	InhA-IN-2

Description	InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 0.31 μM (InhA)[1]
In Vitro	InhA-IN-2 (Compound 23) (200 µM, 48h) inhibits mycolic acid synthesis (33% growth inhibition) in M. tuberculosis H37Ra[1].
References	[1]. Sabbah M, et al. Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. J Med Chem. 2020 May 14;63(9):4749-4761.

Molecular Formula	C₁₆H₁₅ClN₂O₂S₂
Molecular Weight	366.89