894309-72-9

894309-72-9 structure
894309-72-9 structure
  • Name: InhA-IN-4
  • Chemical Name: InhA-IN-4
  • CAS Number: 894309-72-9
  • Molecular Formula: C14H12BrN3O2S
  • Molecular Weight: 366.23
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-09-29 15:29:22
  • Modify Date: 2024-04-09 09:03:44
  • InhA-IN-4 (TU14) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 15.6 μM[1].

Name InhA-IN-4
Description InhA-IN-4 (TU14) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 15.6 μM[1].
Related Catalog
Target

IC50: 15.6 μM (InhA)[1]

In Vitro InhA-IN-4 (TU14) shows antitubercular activity with a MIC of 1.56 ± 0.82 µg/mL against Mycobacterium tuberculosis[1].
References

[1]. Doğan ŞD, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402.

Molecular Formula C14H12BrN3O2S
Molecular Weight 366.23
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