ART-IN-1

Modify Date: 2024-04-06 10:56:55

ART-IN-1 structure	Common Name	ART-IN-1
	CAS Number	2418014-98-7	Molecular Weight	259.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₃NO₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ART-IN-1

ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively[1].

Name	ART-IN-1

Description	ART-IN-1 (compound 7) is a selective PARP inhibitor with IC50s of 19, 22, 2.4, >100, 1.1 µM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	TNKS2:22 μM (IC50) PARP15:1.1 μM (IC50) PARP2:19 μM (IC50) PARP14:>100 μM (IC50) PARP10:2.4 μM (IC50)
In Vitro	ART-IN-1 (compound 7) (0-100 µM) shows inhibition of PARP2, TNKS2, PARP10, PARP14, PARP15 with IC50s of 19, 22, 2.4, >100, 1.1 µM, respectively[1].
References	[1]. Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021;52:116511.

Molecular Formula	C₁₄H₁₃NO₂S
Molecular Weight	259.32

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