Gly-Cyclopropane-Exatecan

Modify Date: 2024-04-06 18:11:19

Gly-Cyclopropane-Exatecan Structure
Gly-Cyclopropane-Exatecan structure
Common Name Gly-Cyclopropane-Exatecan
CAS Number 2414254-49-0 Molecular Weight 619.64
Density N/A Boiling Point N/A
Molecular Formula C32H34FN5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gly-Cyclopropane-Exatecan


Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro[1].

 Names

Name Gly-Cyclopropane-Exatecan

 Gly-Cyclopropane-Exatecan Biological Activity

Description Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan (HY-13631), a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro[1].
Related Catalog
Target

Topoisomerase I

References

[1]. Hua Haiqing, et al. Anti-b7-h4 antibody-drug conjugate and medicinal use thereof: World Intellectual Property Organization, WO2020244657. 2020-12-10.

 Chemical & Physical Properties

Molecular Formula C32H34FN5O7
Molecular Weight 619.64
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Gly-Cyclopropane-Exatecan suppliers

Gly-Cyclopropane-Exatecan price