2414254-52-5

2414254-52-5 structure

Name: MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
Chemical Name: MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
CAS Number: 2414254-52-5
Molecular Formula: C₅₅H₆₀FN₉O₁₃
Molecular Weight: 1074.12
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2023-04-27 16:54:32
Modify Date: 2024-01-11 05:16:55
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

Name	MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

Description	MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
Target	Topoisomerase I
References	[1]. Ying Hua, et al. Anti-B7H3 antibody-exatecan analog conjugate and medicinal use thereof: World Intellectual Property Organization, WO2020063673. 2020-04-02.

Molecular Formula	C₅₅H₆₀FN₉O₁₃
Molecular Weight	1074.12