MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

Modify Date: 2024-01-10 11:16:32

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan Structure
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan structure
Common Name MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
CAS Number 2414254-51-4 Molecular Weight 1074.12
Density N/A Boiling Point N/A
Molecular Formula C55H60FN9O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan


MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].

 Names

Name MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

  Biological Activity

Description MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a drug-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].
Related Catalog
Target

Topoisomerase I

References

[1]. Ying Hua, et al. Anti-B7H3 antibody-exatecan analog conjugate and medicinal use thereof: World Intellectual Property Organization, WO2020063673[P]. 2020-04-02.

 Chemical & Physical Properties

Molecular Formula C55H60FN9O13
Molecular Weight 1074.12