MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan

Modify Date: 2025-09-02 12:38:14

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan Structure
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan structure
Common Name MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
CAS Number 2414393-22-7 Molecular Weight 1074.12
Density N/A Boiling Point N/A
Molecular Formula C55H60FN9O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan


MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a drug-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer[1].

 Names

Name MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan

  Biological Activity

Description MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a drug-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer[1].
Related Catalog
Target

Camptothecins

References

[1]. HUA Haiqing, et al. Antibody-drug conjugate and medical use thereof. Patent WO2021190564A1.

 Chemical & Physical Properties

Molecular Formula C55H60FN9O13
Molecular Weight 1074.12
InChIKey DBCVGCVTFAJVMD-HKMBIKTJSA-N
SMILES CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(F)c(C)c3c1c2C(NC(=O)C1(OCNC(=O)CNC(=O)C(Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O)CCC1)CC3
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