DBCO-C-PEG1

Modify Date: 2024-03-09 20:43:45

DBCO-C-PEG1 Structure
DBCO-C-PEG1 structure
Common Name DBCO-C-PEG1
CAS Number 2377004-09-4 Molecular Weight 362.42
Density N/A Boiling Point N/A
Molecular Formula C22H22N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-C-PEG1


DBCO-C-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-C-PEG1

 DBCO-C-PEG1 Biological Activity

Description DBCO-C-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H22N2O3
Molecular Weight 362.42
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