2377004-09-4

2377004-09-4 structure
2377004-09-4 structure
  • Name: DBCO-C-PEG1
  • Chemical Name: DBCO-C-PEG1
  • CAS Number: 2377004-09-4
  • Molecular Formula: C22H22N2O3
  • Molecular Weight: 362.42
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 22:25:18
  • Modify Date: 2024-03-09 20:43:45
  • DBCO-C-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name DBCO-C-PEG1
Description DBCO-C-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H22N2O3
Molecular Weight 362.42