SGLT inhibitor-1

Modify Date: 2025-08-25 15:21:31

SGLT inhibitor-1 Structure
SGLT inhibitor-1 structure
Common Name SGLT inhibitor-1
CAS Number 2247314-23-2 Molecular Weight 462.46
Density N/A Boiling Point N/A
Molecular Formula C24H27FO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SGLT inhibitor-1


SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].

 Names

Name SGLT inhibitor-1

 SGLT inhibitor-1 Biological Activity

Description SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].
Related Catalog
Target

IC50: 43 nM (hSGLT1), 9 nM (hSGLT2)[1]

References

[1]. Xu G, et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453.

 Chemical & Physical Properties

Molecular Formula C24H27FO8
Molecular Weight 462.46
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