SGLT inhibitor-1

Modify Date: 2024-01-09 19:06:53

SGLT inhibitor-1 structure	Common Name	SGLT inhibitor-1
	CAS Number	2247314-23-2	Molecular Weight	462.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₇FO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SGLT inhibitor-1

SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].

Name	SGLT inhibitor-1

Description	SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT
Target	IC50: 43 nM (hSGLT1), 9 nM (hSGLT2)[1]
References	[1]. Xu G， et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453.

Molecular Formula	C₂₄H₂₇FO₈
Molecular Weight	462.46