Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SGLT inhibitor-1
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2247314-23-2

2247314-23-2 structure

2247314-23-2 structure

Name: SGLT inhibitor-1
Chemical Name: SGLT inhibitor-1
CAS Number: 2247314-23-2
Molecular Formula: C₂₄H₂₇FO₈
Molecular Weight: 462.46
Catalog: Signaling Pathways Membrane Transporter/Ion Channel SGLT
Create Date: 2019-06-29 18:57:05
Modify Date: 2025-08-25 15:21:31
SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].

Name	SGLT inhibitor-1

Description	SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT
Target	IC50: 43 nM (hSGLT1), 9 nM (hSGLT2)[1]
References	[1]. Xu G， et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453.

Molecular Formula	C₂₄H₂₇FO₈
Molecular Weight	462.46

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