IDH1 Inhibitor 2

Modify Date: 2024-01-11 08:16:16

IDH1 Inhibitor 2 Structure
IDH1 Inhibitor 2 structure
Common Name IDH1 Inhibitor 2
CAS Number 2244895-42-7 Molecular Weight 406.48
Density N/A Boiling Point N/A
Molecular Formula C26H22N4O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IDH1 Inhibitor 2


IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1].

 Names

Name IDH1 Inhibitor 2

 IDH1 Inhibitor 2 Biological Activity

Description IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1].
Related Catalog
Target

IC50: 110 nM (IDH1)[1].

References

[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.

 Chemical & Physical Properties

Molecular Formula C26H22N4O
Molecular Weight 406.48