Shanghai Nianxing Industrial Co., Ltd
China
Product Name: IDH1 Inhibitor 3
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2171081-24-4

2171081-24-4 structure

2171081-24-4 structure

Name: IDH1 Inhibitor 3
Chemical Name: IDH1 Inhibitor 3
CAS Number: 2171081-24-4
Molecular Formula: C₃₁H₂₅F₄N₅O₃
Molecular Weight: 591.56
Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
Create Date: 2019-08-04 11:24:59
Modify Date: 2025-08-27 20:28:15
IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1].

Name	IDH1 Inhibitor 3

Description	IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)
Target	IC50: 45 nM (IDH1R132H)[1].
References	[1]. Qiangang Zheng, et al. Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (2017) 5262-5266.

Molecular Formula	C₃₁H₂₅F₄N₅O₃
Molecular Weight	591.56

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