Shanghai Nianxing Industrial Co., Ltd
China
Product Name: IDH1 Inhibitor 2
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Purity: 99.0%
Stocking Period: 10 Day
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2244895-42-7

2244895-42-7 structure

2244895-42-7 structure

Name: IDH1 Inhibitor 2
Chemical Name: IDH1 Inhibitor 2
CAS Number: 2244895-42-7
Molecular Formula: C₂₆H₂₂N₄O
Molecular Weight: 406.48
Catalog: Signaling Pathways Metabolic Enzyme/Protease Isocitrate Dehydrogenase (IDH)
Create Date: 2019-07-01 07:50:15
Modify Date: 2024-01-11 08:16:16
IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1].

Name	IDH1 Inhibitor 2

Description	IDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)
Target	IC50: 110 nM (IDH1)[1].
References	[1]. Jakob CG, et al. Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315. J Med Chem. 2018 Aug 9;61(15):6647-6657.

Molecular Formula	C₂₆H₂₂N₄O
Molecular Weight	406.48

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