DNP-PEG4-DBCO

Modify Date: 2024-04-02 11:25:50

DNP-PEG4-DBCO structure	Common Name	DNP-PEG4-DBCO
	CAS Number	2149585-17-9	Molecular Weight	689.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₅H₃₉N₅O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DNP-PEG4-DBCO

DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DNP-PEG4-DBCO

Description	DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₅H₃₉N₅O₁₀
Molecular Weight	689.71