1801863-88-6

1801863-88-6 structure

Name: (4E)-TCO-PEG4-DBCO
Chemical Name: TCO-PEG4-DBCO
CAS Number: 1801863-88-6
Molecular Formula: C₃₈H₄₉N₃O₈
Molecular Weight: 675.81
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-04-10 19:40:16
Modify Date: 2024-01-09 12:37:07
TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	TCO-PEG4-DBCO

Description	TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Rahim MK, et al. Enhancing reactivity for bioorthogonal pretargeting by unmasking antibody-conjugated trans-cyclooctenes. Bioconjug Chem. 2015 Feb 18;26(2):352-60.