2149585-17-9

2149585-17-9 structure

2149585-17-9 structure

Name: DNP-PEG4-DBCO
Chemical Name: DNP-PEG4-DBCO
CAS Number: 2149585-17-9
Molecular Formula: C₃₅H₃₉N₅O₁₀
Molecular Weight: 689.71
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:19:55
Modify Date: 2024-04-02 11:25:50
DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DNP-PEG4-DBCO

Description	DNP-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₅H₃₉N₅O₁₀
Molecular Weight	689.71