DSPE-PEG4-DBCO

Modify Date: 2024-02-28 03:12:35

DSPE-PEG4-DBCO Structure
DSPE-PEG4-DBCO structure
Common Name DSPE-PEG4-DBCO
CAS Number 2112738-14-2 Molecular Weight 1282.67
Density N/A Boiling Point N/A
Molecular Formula C71H116N3O15P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DSPE-PEG4-DBCO


DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DSPE-PEG4-DBCO
Synonym More Synonyms

 DSPE-PEG4-DBCO Biological Activity

Description DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C71H116N3O15P
Molecular Weight 1282.67

 Synonyms

MFCD30828684